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https://www.blackenterprise.com/male-birth-control-shot-reportedly-passes-clinical-trials/

The Indian Council of Medical Research (ICMR) has successfully completed clinical trials of the world’s first injectable male contraceptive, according to researchers involved in the project, reports BET. 

“The product is ready, with only regulatory approvals pending with the Drugs Controller. The trials are over, including extended, phase 3 clinical trials for which 303 candidates were recruited with a 97.3% success rate and no reported side-effects. The product can safely be called the world’s first male contraceptive,” said Dr. RS Sharma, senior scientist with ICMR, according to The Hindustan Times.

The ICMR, a government-funded biomedical research agency, has created this first-of-its-kind male contraceptive as a replacement for surgical vasectomies. Currently, this is the only method for male sterilization that exists today. It could be made available in seven months if approved and will reportedly last around 13 years.

“It’s the first in the world from India so we have to be extra careful about approval. We are looking at all aspects, especially the good manufacturing practice (GMP) certification that won’t raise any questions about its quality,” said VG Somani, the drug controller general of India.

“I’d say it will still take about six to seven months for all the approvals to be granted before the product can be manufactured,” said Somani. The manufacture, sale, and distribution of new medical innovation in India requires approval from DCGI, which conducts its own checks before clearing it.

The contraceptive is called reversible inhibition of sperm under guidance (RISUG) and is made up of a polymer that is injected into the tubes that carry sperm from the testicles known as the vas deferens.

“Two things are needed from the government for it to work; one is to make use of the trial subjects for awareness generation among masses about the product, and second is to offer higher incentives for people opting for male contraceptives,” says AR Nanda, former family welfare secretary, Government of India.

The Hindustan Times announced it on their Twitter account, “The contraceptive is designed as a replacement for surgical vasectomy, which is the only male sterilization method available in the world.

November 27, 2019

Male Birth Control Shot Reportedly Passes Clinical Trials

https://www.blackenterprise.com/male-birth-control-shot-reportedly-passes-clinical-trials/

The Indian Council of Medical Research (ICMR) has successfully completed clinical trials of the world’s first injectable male contraceptive, according to researchers involved in the project, reports BET. 

“The product is ready, with only regulatory approvals pending with the Drugs Controller. The trials are over, including extended, phase 3 clinical trials for which 303 candidates were recruited with a 97.3% success rate and no reported side-effects. The product can safely be called the world’s first male contraceptive,” said Dr. RS Sharma, senior scientist with ICMR, according to The Hindustan Times.

The ICMR, a government-funded biomedical research agency, has created this first-of-its-kind male contraceptive as a replacement for surgical vasectomies. Currently, this is the only method for male sterilization that exists today. It could be made available in seven months if approved and will reportedly last around 13 years.

“It’s the first in the world from India so we have to be extra careful about approval. We are looking at all aspects, especially the good manufacturing practice (GMP) certification that won’t raise any questions about its quality,” said VG Somani, the drug controller general of India.

“I’d say it will still take about six to seven months for all the approvals to be granted before the product can be manufactured,” said Somani. The manufacture, sale, and distribution of new medical innovation in India requires approval from DCGI, which conducts its own checks before clearing it.

The contraceptive is called reversible inhibition of sperm under guidance (RISUG) and is made up of a polymer that is injected into the tubes that carry sperm from the testicles known as the vas deferens.

“Two things are needed from the government for it to work; one is to make use of the trial subjects for awareness generation among masses about the product, and second is to offer higher incentives for people opting for male contraceptives,” says AR Nanda, former family welfare secretary, Government of India.

The Hindustan Times announced it on their Twitter account, “The contraceptive is designed as a replacement for surgical vasectomy, which is the only male sterilization method available in the world.


November 27, 2019

Top Tech Deals From Amazon’s Pre-Black Friday Ad

https://www.geek.com/deals-2/top-tech-deals-from-amazons-pre-black-friday-ad-1811983/?source

Amazon's pre-Black Friday ad features many deals on Alexa devices, Fire tablets, and more electronics. (Photo Credit: Amazon)

Black Friday is only a few days away and Amazon is getting an early start on the shopping holiday. If you or someone else on your list needs a new Fire TV Stick, a tablet, or smart doorbell system, Amazon is offering discounts on a lot of tech products.

The best part? You can make all your purchases online. No lines, crowds, or limited parking are involved. And, our sister site BestBlackFriday.com says Amazon is dropping some promotions before Nov. 29. Of course, you can also wait until Black Friday to enjoy sales on all your favorite electronics.

Below are the best tech deals from Amazon’s pre-Black Friday ad. If you want a general scope of Black Friday 2019, check out our brief forecast, or if you want to explore some great Black Friday gift options, read our roundup here.

Tech Deals

Photo Credit: Amazon

All-New Fire HD 10 Tablet for $99.99 (Save $50)

Fire Stick 4K With Alexa Voice Remote for $24.99 (Save $25)

Echo Show 5 for $49.99 (Save $40)

All-New Fire 7 Tablet for $29.99 (Save $20)

Photo Credit: Amazon

Ring Video Doorbell Pro with Echo Show 5 for $189 (Save $139.99)

Amazon Smart Plug (w/Bundle Purchase) for $4.99 (Save $20)

Fire HD 8 Tablet for $49.99 (Save $30)

Photo Credit: Amazon

New Kindle Paperwhite for $84.99 (Save $45)

Echo Dot (3rd Gen) for $22 (Save $37.99)

Blink XT2 Outdoor/Indoor Security Camera for $184.99 (Save $65)

For more deals, including all of the latest Black Friday announcements, check out our sister site, BestBlackFriday.com.

More on Geek.com:


November 26, 2019

Things We Saw Today: The First Official Baby Yoda Merchandise Is Not Great

https://www.themarysue.com/first-official-baby-yoda-merchandise-is-not-great/

baby yoda ior something like it n the mandalorian

After the explosive popularity of The Mandalorian‘s “The Child,” aka Baby Yoda, aka New God of the Internet, we wondered how best to express our devotion. Under late capitalism, this usually takes the form of buying overpriced things and displaying them prominently on our desks and bodies. Unfortunately for our hearts and wallets, the first official offerings from Star Wars’ Disney overlords reek of a rush job.

Disney was clearly caught off-guard by the demand to own a piece of Baby Yoda all our own. The character was kept top-secret, which means that toys were not planned in advance, presumably to prevent leaks (which can often come in toy form). This is understandable. However, it seems clear from the merch finally put on offer today via an announcement on StarWars.com that Disney really just had no idea Baby Yoda was going to take off the way it did. They seem to have had no toy or merchandise design plans waiting in the wings.

Hasbro confirmed to Vanity Fair that there will be no Baby Yoda toys come Christmastime, and toys will not appear until sometime in 2020. Considering how many Baby Yoda toys they could sell at the moment for the holiday season, this seems like a huge oversight. You have to strike while the Baby Yoda is still hot. Will we even remember who Baby Yoda is by, say, March? Questions abound.

What has now been put forward is a single concept art image from series concept supervisor Christian Alzmann (the image itself is perfectly cool and adorable, but they have offered just the one), and then they just kind of …. slapped it on a bunch of generic stuff. T-shirts, stickers, mugs, totes, phone cases, popsockets, etc.

The line looks like items I’d expect to see for sale by fan artists on sale at a Redbubble account, only most fan artists I know would have done much more thoughtful and nuanced work. StarWars.com promises more merch to come, of which I have little doubt, but this put a bad taste in my mouth.

I understand a rush to capitalize, but maybe the giant megacorporation that employs some of the finest artists and graphic artists in the business could maybe pause a minute and make some merch we’d more happily splash out on?

(via StarWars.com, images: Disney)

  • Grease spin-off series has been ordered by HBO, because God is dead. (Not you, Baby Yoda! Never you.) (via Deadline)
  • Imelda Staunton could possibly replace Olivia Colman in The Crown‘s later seasons, which is a glorious idea even if I will hate Dolores Umbridge forever. (via Hollywood Reporter)
  • A capybaras-only coloring book may be a better use of your money than a bad Baby Yoda t-shirt. (via BoingBoing)
  • Is the release of a Snyder Justice League cut only a pipe dream? (via Comicbook)
  • Meanwhile, DC seems to be plotting far into its future, and the best bit of intel is that Michael B. Jordan took a meeting with them to talk Superman. Unfortunately, we’d probably not see Jordan’s Superman, if it were to happen, for many years. (via Variety)
  • The President is an idiot, exhibit #8,9062.

What did you see today?

Want more stories like this? Become a subscriber and support the site!

The Mary Sue has a strict comment policy that forbids, but is not limited to, personal insults toward anyone, hate speech, and trolling.—


November 26, 2019

Oprah Winfrey Announced Star-Studded Line Up For Oprah’s 2020 Vision: Your Life in Focus Tour

https://www.blackenterprise.com/oprah-winfrey-weight-watchers-2020-vision-tour-special-guests/

Oprah Winfrey and Weight Watchers have announced the special guests they have lined up for Oprah’s 2020 Vision: Your Life in Focus Tour, starting in January 2020.

Oprah will sit down for an intimate one-on-one conversation with Lady Gaga in Ft. Lauderdale, Florida; Tina Fey in St. Paul, Minnesota; Amy Schumer in Charlotte, North Carolina; Dwayne “The Rock”  Johnson in Atlanta; Michelle Obama in Brooklyn, New York; Tracee Ellis Ross in Dallas; Kate Hudson in San Francisco; Jennifer Lopez in Los Angeles; and Gayle King in Denver. Tickets are on sale now at ticketmaster.com.

“What I know for sure is we can all come together to support a stronger, healthier, more abundant life—focused on what makes us feel energized, connected and empowered,” Winfrey said in a statement. “As I travel the country, my hope for this experience is to motivate others to let 2020 be the year of transformation and triumph—beginning first and foremost with what makes us well. This is the year to move forward, let’s make it happen in 2020.”

Over $1 million from tour proceeds will benefit WW Good, the philanthropic arm of WW that helps bring fresh, healthy food to underserved communities nationwide.

OPRAH’S 2020 VISION: YOUR LIFE IN FOCUS:

DATE

CITY

VENUE

INTERVIEW GUEST

Sat Jan 04

Ft. Lauderdale, FL

BB&T Center

Lady Gaga

Sat Jan 11

St. Paul, MN

Xcel Energy Center

Tina Fey

Sat Jan 18

Charlotte, NC

Spectrum Center

Amy Schumer

Sat Jan 25

Atlanta, GA

State Farm Arena

Dwayne Johnson

Sat Feb 08

Brooklyn, NY

Barclays Center

Michelle Obama

Sat Feb 15

Dallas, TX

American Airlines Center

Tracee Ellis Ross

Sat Feb 22

San Francisco, CA

Chase Center

Kate Hudson

Sat Feb 29

Los Angeles, CA

The Forum

Jennifer Lopez

Sat Mar 07

Denver, CO

Pepsi Center

Gayle King

 

Oprah’s 2020 Vision: Your Life in Focus Tour is presented and produced by WW, led by Amy Weinblum, chief business development officer and Oprah’s former chief of staff, who is overseeing the launch of WW’s live events & experiences business. The show is executive produced by Emmy Award-winning producer Jenna Kostelnik Utley, WW’s SVP, Content, Production & Experiences and former executive producer for Oprah. The tour is produced in conjunction with Live Nation’s Women Nation, the newly formed division dedicated to women-driven live events led by Ali Harnell, president and chief strategy officer, Women Nation.


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